Study of the blood-aqueous barrier in choroidal melanoma.

Corneal autofluorescence in choroidal melanoma or in choroidal naevus.

AIMS To investigate whether corneal autofluorescence is different in patients with choroidal melanoma or choroidal naevus. METHODS Corneal autofluorescence was determined by fluorophotometry in both eyes of 32 patients with a unilateral choroidal melanoma, 32 patients with a unilateral choroidal naevus, and 32 age matched healthy controls. The corneal autofluorescence ratio between affected a...

Fulminant hepatic failure due to metastatic choroidal melanoma

Diffusion MRI of Choroid Melanoma Tumor in Mouse Eye

Introduction Choroidal melanoma is the most common intraocular malignancy . Diffusion weighted MRI (DWI) and the derived apparent diffusion coefficient (ADC) map has proven to be useful in tumor identification and treatment response monitoring . However, DWI of intraocular tumor, such as choroidal melanoma, has not been reported to date. The objective of the present study is to quantify ADC of ...

ET-1 Plasma Levels, Aqueous Flare, and Choroidal Thickness in Patients with Retinitis Pigmentosa

Purpose. To assess endothelin-1 (ET-1) plasma levels, choroidal thickness, and aqueous flare in patients with early stage retinitis pigmentosa (RP) and to search for possible correlations. Methods. We compared 24 RP patients with 24 healthy controls. Choroidal thickness and aqueous flare were measured, respectively, by using a spectral domain optical coherence tomography and a laser flare-cell ...

Hemodynamic parameters in blood vessels in choroidal melanoma xenografts and rat choroid.

PURPOSE Choroidal melanoma is the most common primary ocular cancer among the adult population. To avoid enucleation, there has been a concerted effort to develop therapies that spare the affected eye and the patient's vision. Blood flow helps shape the tumor's microenvironment, plays a key role in the tumor's response to many different types of therapy, and is necessary for delivery of chemoth...